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Blood tests for bladder cancer

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(@soahm)
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Which blood tests are performed in the diagnosis of bladder cancer? 

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(@rohini)
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Blood tests are not typically the primary diagnostic tool for bladder cancer, as the detection and diagnosis of bladder cancer often involve other specific tests, such as imaging studies, cystoscopy, and urine tests. However, blood tests may be used as part of the overall assessment of a person with suspected or diagnosed bladder cancer. These tests can provide valuable information about the general health of the individual and help in monitoring the effects of treatment. Here are some blood tests that may be relevant in the context of bladder cancer:

  1. Complete Blood Count (CBC):

    • A CBC measures the number and types of blood cells, including red blood cells, white blood cells, and platelets. It helps assess overall health and detect conditions such as anemia or infections.
  2. Blood Chemistry Panel:

    • A blood chemistry panel includes various tests that assess the levels of electrolytes, liver enzymes, kidney function, and other substances in the blood. Abnormalities in these levels may provide information about the impact of cancer on organ function or the effects of cancer treatments.
  3. Liver Function Tests:

    • Liver function tests, including tests for enzymes such as alanine transaminase (ALT) and aspartate transaminase (AST), can help evaluate the health of the liver. Bladder cancer that has metastasized to the liver may affect these values.
  4. Kidney Function Tests:

    • Blood urea nitrogen (BUN) and creatinine tests assess kidney function. Bladder cancer or its treatment can sometimes impact kidney function, so these tests may be monitored during the course of the disease.
  5. C-Reactive Protein (CRP):

    • CRP is a marker of inflammation in the body. Elevated levels may indicate inflammation, which can be associated with cancer or other health conditions.
  6. Coagulation Tests:

    • Bladder cancer patients may undergo coagulation tests to assess the blood's ability to clot. Certain cancer treatments, such as chemotherapy, can affect clotting factors.

While blood tests are helpful for assessing overall health and monitoring potential side effects of bladder cancer and its treatments, the diagnosis of bladder cancer typically relies on more specific methods. These may include:

  • Urine Cytology: Examining urine under a microscope to detect abnormal cells shed by the bladder tumor.

  • Cystoscopy: A procedure using a thin, flexible tube with a camera to visualize the inside of the bladder.

  • Imaging Studies: X-rays, CT scans, MRIs, or other imaging techniques to visualize the bladder and surrounding structures.

  • Biopsy: Removal of a small sample of tissue from the bladder for examination under a microscope.

If you suspect bladder cancer or have been diagnosed, it's essential to work closely with your healthcare team, which may include urologists, oncologists, and other specialists, to determine the most appropriate diagnostic and monitoring strategies for your specific situation.

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