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How does blood cancer affect blood cell counts?

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(@komal)
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How does blood cancer affect blood cell counts?
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Blood cancer, including leukemia, lymphoma, and multiple myeloma, can affect blood cell counts in several ways due to the abnormal growth and behavior of cancerous cells in the bone marrow. Here's a simple explanation of how blood cancer can impact blood cell counts:

Red Blood Cells (RBCs):

  • Blood cancer can lead to a decrease in red blood cell production or cause the destruction of red blood cells in the bloodstream.
  • Low red blood cell counts, known as anemia, can result in symptoms such as fatigue, weakness, pale skin, and shortness of breath.

White Blood Cells (WBCs):

  • Blood cancer can cause an increase or decrease in white blood cell production, depending on the type of cancer and its stage.
  • In leukemia, for example, abnormal white blood cells (leukemic blasts) crowd out normal blood cells in the bone marrow, leading to a decrease in healthy white blood cells.
  • Conversely, in some cases of leukemia or lymphoma, there may be an increase in white blood cells due to the proliferation of cancerous cells.
  • Changes in white blood cell counts can affect the body's ability to fight infections, leading to increased susceptibility to infections or frequent infections.

Platelets:

  • Blood cancer can also affect platelet production in the bone marrow.
  • Low platelet counts, known as thrombocytopenia, can result in symptoms such as easy bruising, excessive bleeding from minor injuries, and prolonged bleeding after cuts or dental work.

Bone Marrow Function:

  • Blood cancer can disrupt normal bone marrow function, impairing its ability to produce adequate numbers of healthy blood cells.
  • This disruption can lead to abnormalities in blood cell counts, including low red blood cells, white blood cells, and platelets.

Regular blood tests, such as complete blood count (CBC) tests, are used to monitor blood cell counts in individuals with blood cancer. Managing blood cell counts is an important aspect of treatment for blood cancer to prevent complications such as anemia, infections, and bleeding disorders. Treatment approaches may include chemotherapy, radiation therapy, targeted therapy, and stem cell transplantation, depending on the type and stage of blood cancer.

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