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What causes blood cancer?

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(@komal)
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What causes blood cancer?
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(@rohini)
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Blood cancer, like leukemia, lymphoma, and multiple myeloma, is caused by genetic mutations or alterations in the DNA of blood cells. Here's a simple explanation:

Genetic Mutations: Mutations in the DNA of blood cells can disrupt normal cell growth and division, leading to the uncontrolled proliferation of abnormal cells characteristic of blood cancer. These mutations may occur spontaneously or be inherited from parents.

Environmental Factors: Exposure to certain environmental factors, such as radiation, benzene (a chemical found in tobacco smoke and industrial settings), certain pesticides, and chemotherapy drugs used to treat other cancers, can increase the risk of developing blood cancer. These factors can damage DNA and trigger mutations that contribute to the development of cancer.

Viral Infections: Infections with certain viruses, such as Epstein-Barr virus (EBV), human T-cell lymphotropic virus (HTLV-1), hepatitis B virus (HBV), hepatitis C virus (HCV), and human papillomavirus (HPV), have been linked to an increased risk of blood cancer. These viruses can disrupt normal cellular processes and promote the growth of cancerous cells.

Immune System Disorders: Conditions that weaken the immune system, such as HIV/AIDS, autoimmune diseases, and organ transplantation, may increase the risk of developing blood cancer. A compromised immune system may fail to detect and destroy abnormal cells, allowing them to proliferate unchecked.

While these factors can increase the risk of developing blood cancer, it's important to note that not everyone exposed to these factors will develop the disease. The interplay of genetic, environmental, and lifestyle factors in blood cancer development is complex, and ongoing research aims to better understand these mechanisms to improve prevention and treatment strategies.

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